What Term Is Used to Describe a Soluble Base

Clearly the acidbase characteristics of compounds within drug discovery have been looked at however ionisation constants appear to have been largely under-scrutinised. The sections below specifically examine the evidence where acidbase properties have been shown to affect particular attributes of compound behaviour.

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The term base appears to have been first used in 1717 by the French chemist Louis Lémery as a synonym for the older Paracelsian term matrix In keeping with 16th-century animism Paracelsus had postulated that naturally occurring salts grew within the earth as a result of a universal acid or seminal principle having impregnated an earthy matrix or womb.

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